Indication for Liver Transplant

Indications for liver transplant

Patients with Chronic liver disease having following signs & symptoms are usually referred for Liver transplantation

MELD > 15
CTP > 8

• Ascites (water in the ‘tummy’)
• Hepatic encephalopathy (Excessive sleepiness, drowsiness, mental confusion)
• Hepatorenal syndrome (Chronic liver disease with ascites & raised Creatinine level)
• Upper GI bleed, (Bloody vomiting or Black stools) Refractory to endoscopic management
• Spontaneous bacterial peritonitis
• Progressive malnutrition/Growth retardation
• Jaundice
• Hepatocellular carcinoma

Indication for Liver Transplant in Children

In children, the most common reason for liver transplantation is biliary atresia.
Other diseases that progress to End-stage liver disease(ESLD) among pediatric patients and require liver transplantation include a variety of metabolic disorders. These include:

• Wilson’s disease
• Alpha 1-antitrypsin deficiency
• Tyrosinemia
• Hemochromatosis
• Crigler-Najjar syndrome
• Glycogen storage disorder
• Hyperoxaluria
• Metabolic respiratory chain deficiencies
• Familial hypercholesterolemia

Can anyone with liver problems get a transplant?

You cannot have a transplant if you have:

• Cancer in another part of your body
• Serious heart, lung, or nerve disease
• Active alcohol or illegal drug abuse
• An active, severe infection
• Inability to follow your doctor's instructions