Indication for Liver Transplant

Indications for liver transplant

Patients with Chronic liver disease having following signs & symptoms are usually referred for Liver transplantation

MELD > 15
CTP > 8

  • Ascites (water in the ‘tummy’)
  • Hepatic encephalopathy (Excessive sleepiness, drowsiness, mental confusion)
  • Hepatorenal syndrome (Chronic liver disease with ascites & raised Creatinine level)
  • Upper GI bleed, (Bloody vomiting or Black stools) Refractory to endoscopic management
  • Spontaneous bacterial peritonitis
  • Progressive malnutrition/Growth retardation
  • Jaundice
  • Hepatocellular carcinoma

Indication for Liver Transplant in Children

In children, the most common reason for liver transplantation is biliary atresia.
Other diseases that progress to End-stage liver disease(ESLD) among pediatric patients and require liver transplantation include a variety of metabolic disorders. These include:

  • Wilson’s disease
  • Alpha 1-antitrypsin deficiency
  • Tyrosinemia
  • Hemochromatosis
  • Crigler-Najjar syndrome
  • Glycogen storage disorder
  • Hyperoxaluria
  • Metabolic respiratory chain deficiencies
  • Familial hypercholesterolemia
  • Can anyone with liver problems get a transplant?

    You cannot have a transplant if you have:

    • Cancer in another part of your body
    • Serious heart, lung, or nerve disease
    • Active alcohol or illegal drug abuse
    • An active, severe infection
    • Inability to follow your doctor's instructions